Low pressure hydrocephalus (LPH)

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Low pressure hydrocephalus (LPH). This is ventriculomegaly with inappropriately low intracranial pressure. Fully referenced neurology checklist.

Pathology

  • This is ventriculomegaly with inappropriately low intracranial pressure
  • The intracranial pressure is usually ≤ 5 to 8 cm H2O
  • The symptoms are typical of raised intracranial pressure
  • The symptoms may result from brainstem compression by enlarged SCF spaces

Possible pathogenesis

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Causes and risk factors

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Clinical features

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Pang and Altschuler diagnostic criteria

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Treatment

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Synonyms

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Acronym

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References

  1. Keough MB, Isaacs AM, Urbaneja G, Dronyk J, Lapointe AP, Hamilton MG. Acute low-pressure hydrocephalus: a case series and systematic review of 195 patients. J Neurosurg 2020 (Online ahead of print).
  2. Hamilton MG, Price AV. Syndrome of inappropriately low-pressure acute hydrocephalus (SILPAH). Acta Neurochir Suppl 2012; 113:155-159.
  3. Duan S, Hu J. Pathogenesis and management of low-pressure hydrocephalus: A narrative review. J Neurol Sci 2024; 460:122988.
  4. Michael AP, Elkouzi A, Elble RJ. Pearls & Oy-sters: Low-pressure hydrocephalus and inadequate shunting. Neurology 2017; 88:e174-e177.
  5. Vilela MD, Pedrosa HA, Mesquita BF, Horiguchi CLF. Low-pressure hydrocephalus and shunt malfunction following a lumbar puncture in an adult reversed by an epidural blood patch. World Neurosurg 2020; 143:56-61.
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