Low grade gliomas: management
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Low grade gliomas: management. 11C-methionine (MET): this distinguishes glioma from non-tumour. Fully referenced neurology checklist.
Positron emission tomography (PET)
- 11C-methionine (MET): this distinguishes glioma from non-tumour
- FDG: this detects malignant transformation of astrocytoma
- PET with 1p/19q loss: this is a marker of oligodendroglioma and oligoastrocytoma
Magnetic resonance spectroscopy (MRS)
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Conservative treatment therapy: indications
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Surgery: indications
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Surgery: benefits
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Post-operative Temozolomide: indications
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Post-operative radiotherapy
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MRI surveillance: indications
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References
- Soffietti R, Baumert BG, Bello L, et al. Guidelines on management of low-grade gliomas: report of an EFNS-EANO Task Force. Eur J Neurol 2010; 17:1124-1133.
- Pouratian N, Schiff D. Management of low-grade glioma. Curr Neurol Neurosci Rep 2010; 10:224-231.
- Pouratian N, Schiff D. Management of low grade glioma. Curr Neurol Neurosci Rep 2010; 10:224-231.
- Delgado-López PD, Corrales-García EM, Martino J, Lastra-Aras E, Dueñas-Polo MT. Diffuse low-grade glioma: a review on the new molecular classification, natural history and current management strategies. Clin Transl Oncol 2017; 19:931-944.
- Kerrigan S, Grant R. Low-grade brain tumours and seizures. Pract Neurol 2012; 12:72-76.
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