Long lasting autonomic symptoms with associated hemicrania (LASH): clinical features

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Long lasting autonomic symptoms with associated hemicrania (LASH): clinical features. This is a trigeminal autonomic cephalalgia (TAC).

Definition

  • This is a trigeminal autonomic cephalalgia (TAC)
  • It is an Indomethacin-responsive headache

Triggers

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Clinical features

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Autonomic features

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Treatment

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References

  1. Donnet A, Lucas C, Massardier E, Boulliat J. Hemicrania with response to indomethacin and prevalent autonomic symptoms: four cases. Cephalalgia 2003; 23:157-160.
  2. Rozen TD, Beams JL. A case of post-traumatic LASH syndrome responsive to indomethacin and melatonin (a man with a unique triad of indomethacin-responsive trigeminal autonomic cephalalgias). Cephalalgia 2015; 35:453-456.
  3. Rozen TD. LASH syndrome: new cases with a broadening clinical phenotype. Cephalalgia 2019; 39:1595-1600. 

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