Leprosy associated neuropathy
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Leprosy associated neuropathy. This is the most common presentation. Overlying skin lesions increase the risk. Fully referenced neurology checklist.
Mononeuritis multiplex
- This is the most common presentation
- Overlying skin lesions increase the risk
- It is typically a small fiber neuropathy
- The upper limbs are more frequently affected
- Autonomic involvement may be prominent
Other neuropathy types
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Associated clinical features
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Differential diagnosis
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Nerve conduction studies (NCS)
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Other investigations
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References
- Nascimento OJ. Leprosy neuropathy: clinical presentations. Arq Neuropsiquiatr 2013; 71:661-666.
- Ooi WW, Srinivasan J. Leprosy and the peripheral nervous system: basic and clinical aspects. Muscle Nerve 2004; 30:393-409.
- Galtrey CM, Modarres H, Jaunmuktane Z, et al. Leprosy in a patient infected with HIV. Pract Neurol 2017; 17:135-139.
- van Brakel WH, Nicholls PG, Das L, Barkataki P, et al. The INFIR Cohort Study: investigating prediction, detection and pathogenesis of neuropathy and reactions in leprosy. Methods and baseline results of a cohort of multibacillary leprosy patients in north India. Lepr Rev 2005; 76:14-34.
- Cabalar M, Yayla V, Ulutas S, Senadim S, Oktar AC. The clinical & neurophysiological study of leprosy. Pak J Med Sci 2014; 30:501-506.
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