Landau-Kleffner syndrome (LKS): management
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Landau-Kleffner syndrome (LKS): management. The EEG shows repetitive spikes and spikes and slow waves. Fully referenced neurology checklist.
Electroencephalogram (EEG)
- The EEG shows repetitive spikes and spikes and slow waves
- These are unilateral, bilateral, or multifocal
Other investigations
Locked: subscribe to see this section.
Treatment
Locked: subscribe to see this section.
AEDs which may worsen seizures
Locked: subscribe to see this section.
References
- Appleton RE. The Landau-Kleffner syndrome. Arch Dis Child 1995; 72:386–387.
- Nieuwenhuis L, Nicolai J. The pathophysiological mechanisms of cognitive and behavioral disturbances in children with Landau-Kleffner syndrome or epilepsy with continuous spike-and-waves during slow-wave sleep. Seizure 2006; 15:249-258.
- Cole AJ, Andermann F, Taylor L, et al. The Landau-Kleffner syndrome of acquired epileptic aphasia: Unusual clinical outcome, surgical experience, and absence of encephalitis. Neurology 1988; 38:31-38.
- Santos LH, Antoniuk A, Rodrigues M, Bruno S, Bruck I. Landau-Kleffner syndrome: study of four cases. Arq Neuropsiquiatr 2002; 60:239-241.
- Marescaux C, Hirsch E, Finck S, et al. Landau-Kleffner syndrome: a pharmacologic study of five cases. Epilepsia 1990; 31:768-777.
