Lacosamide: adverse effects
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Lacosamide: adverse effects. Headache, Dizziness, Diplopia, Vertigo, Ataxia, Tremor, Tics, Worsening of seizures. Fully referenced neurology checklist.
Neurological side effects
- Headache
- Dizziness
- Diplopia
- Vertigo
- Ataxia
- Tremor
- Tics
- Worsening of seizures
- HyperCKaemia
- Dyskinesias
Psychiatric side effects
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Cardiac side effects
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Systemic side effects
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References
- Hoy SM. Lacosamide: a review of its use as adjunctive therapy in the management of partial-onset seizures. CNS Drugs 2013; 27:1125-1142.
- Zaccara G, Perucca P, Loiacono G, Giovannelli F, Verrotti A. The adverse event profile of lacosamide: a systematic review and meta-analysis of randomized controlled trials. Epilepsia 2013; 54:66-74.
- Krauss G, Ben-Menachem E, Mameniskiene R, et al; SP757 Study Group. Intravenous lacosamide as short-term replacement for oral lacosamide in partial-onset seizures. Epilepsia 2010; 51:951-957.
- Guilhoto LM, Loddenkemper T, Gooty VD, et al. Experience with lacosamide in a series of children with drug-resistant focal epilepsy. Pediatr Neurol 2011; 44:414-419.
- Matsudaira T, Terada T, Araki Y, Ikeda H, Obi T, Inoue Y. HyperCKemia associated with lacosamide therapy in an elderly patient with focal onset epilepsy. Seizure 2018; 63:14-16.
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