Korsakoff syndrome

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Korsakoff syndrome. Thiamine deficiency, Chronic alcohol misuse, Non-alcoholic cases of thiamine deficiency. Fully referenced neurology checklist.

Risk factors

  • Thiamine deficiency
  • Chronic alcohol misuse
  • Non-alcoholic cases of thiamine deficiency
  • Carbon monoxide (CO) poisoning
  • Lead poisoning
  • Arsenic poisoning
  • Diabetes mellitus
  • Infections
  • Possible genetic predisposition

Clinical features

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Associated features

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Magnetic resonance imaging (MRI) lesions: locations

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Synonym

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References

  1. Kopelman MD, Thimson AD, Guerrini I, Marshall EJ. The Korsakoff syndrome: clinical aspects, psychology and treatment. Alcohol Alcohol 2009; 44:148-154.
  2. Blansjaar BA, van Dijk JG. Korsakoff minus Wernicke syndrome. Alcohol Alcohol 1992; 4:435-437.
  3. Wijnia JW, Oudman E, Batjes DM, Brouwer BA, Oey M, Postma A. Korsakoff syndrome and altered pain perception: a search of underlying neural mechanisms. Scand J Pain 2022; 23:424-432.

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