Ischaemic stroke: medical risk factors

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Ischaemic stroke: medical risk factors. High potassium, High sodium to potassium ratio, High homocysteine. Fully referenced neurology checklist.

Metabolic risk factors

  • High potassium
  • High sodium to potassium ratio
  • High homocysteine
  • β2 microglobulin: in women
  • Hyperlipidemia
  • Long-chain dicarboxylic acids: tetradecanedioate and hexadecanedioate
  • Proteinuria

Infections

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Drugs

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Other risk factors

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Possible protective factors

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References

  1. Johnson LS, Mattsson N, Sajadieh A, Wollmer P, Söderholm M. Serum potassium is positively associated with stroke and mortality in the large, population-based malmö preventive project cohort. Stroke 2017; 48:2973-2978.
  2. Willey J, Gardener H, Cespedes S, Cheung YK, Sacco RL, Elkind MSV. Dietary sodium to potassium ratio and risk of stroke in a multiethnic urban population: The Northern Manhattan Study. Stroke 2017; 48:2979-2983.
  3. Huang X, Li Y, Li P, et al. Association between percent decline in serum total homocysteine and risk of first stroke. Neurology 2017; 89:2101-2107.
  4. Rist PM, Jiménez MC, Rexrode KM. Prospective association between β2-microglobulin levels and ischemic stroke risk among women. Neurology 2017; 88:2176-2182.
  5. Sun D, Tiedt S, Yu B, et al. A prospective study of serum metabolites and risk of ischemic stroke. Neurology 2019; 92:e1890-e1898.
  6. And 24 more. Subscribe to see the full list

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