Ischaemic stroke: hand knob syndrome

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Ischaemic stroke: hand knob syndrome. This is stroke presentation as isolated hand weakness. Fully referenced neurology checklist.

Pathology

  • This is stroke presentation as isolated hand weakness
  • It is caused by stroke or lesions in the precentral gyrus
  • This is the hand knob area

Frequent causes

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Clinical features

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Differential diagnosis

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References

  1. Orosz P, Szőcs I, Rudas G, Folyovich A, Bereczki D, Vastagh I. Cortical hand knob stroke: report of 25 cases. J Stroke Cerebrovasc Dis 2018; 27:1949-1955. 
  2. Alshanqiti MA, Alharbi N, Althobaiti FA, et al. Hand knob syndrome secondary to ipsilateral concomitant carotid fibromuscular dysplasia and proximal atherosclerotic disease. Cureus 2023; 15:e40072.
  3. Rissardo JP, Byroju VV, Mukkamalla S, Caprara ALF. A narrative review of stroke of cortical hand knob area. Medicina (Kaunas) 2024; 60:318.
  4. Finkelsteyn AM, Saucedo MA, Miquelini LA, et al. Ischemic stroke of the "hand knob area": a case series and literature review. J Clin Neurosci 2019; 65:100-105.
  5. Chapur J, Kojic K, Kula M, Flexman AM. Perioperative cortical hand stroke syndrome mimicking peripheral neuropathy: a case report. Can J Anaesth 2023; 70:1839-1844.
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