Intracranial arterial dolichoectasia (IADE): pathology

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Intracranial arterial dolichoectasia (IADE): pathology. These are dilated and elongated arteries. Fully referenced neurology checklist.

Gross pathology

  • These are dilated and elongated arteries
  • They have an increased vessel diameter (ectasis)
  • They follow a long and tortuous course (dolichosis)
  • 80% involve the basilar artery

Microscopic pathology

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Diagnostic arterial diameter cut-off

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Defining features of basilar arterial elongation

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Synonyms

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Gross pathology

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Microscopic pathology

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Diagnostic arterial diameter cut-off

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Defining features of basilar arterial elongation

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Synonyms

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References

  1. Del Brutto VJ, Ortiz JG, Biller J. Intracranial arterial dolichoectasia. Front Neurol 2017; 8:344. 
  2. Pico F, Labreuche J, Amarenco P. Pathophysiology, presentation, prognosis, and management of intracranial arterial dolichoectasia. Lancet Neurol 2015; 14:833-845.
  3. Passero SG, Rossi S. Natural history of vertebrobasilar dolichoectasia. Neurology 2008; 70:66-72. 
  4. Smoker WR, Price MJ, Keyes WD, Corbett JJ, Gentry LR. High-resolution computed tomography of the basilar artery: 1. Normal size and position. Am J Neuroradiol 1986; 7:55-60.
  5. Del Brutto VJ, Ortiz JG, Biller J. Intracranial arterial dolichoectasia. Front Neurol 2017; 8:344. 
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