Insular seizures

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Insular seizures. The insula is also known as the Island of Reil. It is located at the base of the Sylvian fissure. Fully referenced neurology checklist.

The insula: anatomy

  • The insula is also known as the Island of Reil
  • It is located at the base of the Sylvian fissure
  • It is beneath the frontal, temporal, and parietal opercula
  • It consists of an anterior and a posterior part
  • It is supplied by the middle cerebral artery
  • It has connections with the limbic system, basal ganglia, and thalamus

The insula: function

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Cardiorespiratory features

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Sensory and autonomic features

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Motor features

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Complications

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Differential diagnosis

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Autoimmune associations

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Investigations

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Treatment

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References

  1. Wynford-Thomas R, Powell R. Navigating the Island of Reil: how to understand the insular cortex. Pract Neurol 2017; 17:122-126. 
  2. Kurukumbi M, Leiphart J, Singer L. A rare case of insular epilepsy: not to be missed in refractory epilepsy patients. Cureus 2019; 11:e5434. 
  3. Isnard J, Guénot M, Sindou M, Mauguière F. Clinical manifestations of insular lobe seizures: a stereo-electroencephalographic study. Epilepsia 2004; 45:1079-1090.
  4. Isnard J, Hagiwara K, Montavont A, et al. Semiology of insular lobe seizures. Rev Neurol (Paris) 2019; 175:144-149. 
  5. Jobst BC, Gonzalez-Martinez J, Isnard J, et al. The insula and its epilepsies. Epilepsy Curr 2019; 19:11-21.
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