Immune mediated necrotizing inflammatory myopathy antibodies
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Immune mediated necrotizing inflammatory myopathy antibodies. This is 3-hydroxy-3-methylglutaryl-CoA reductase. Fully referenced neurology checklist.
HMGCoA reductase
- This is 3-hydroxy-3-methylglutaryl-CoA reductase
- It is typically caused by Statins
- It is associated with cancer in adults
- It responds to IVIg: this is preferable to Rituximab
- Also see Neurochecklists: “Immune mediated necrotising myopathy (IMNM)”
SRP
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Acronym
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References
- Rietveld A, Lim J, de Visser M, et al. Autoantibody testing in idiopathic inflammatory myopathies. Pract Neurol 2019; pii: practneurol-2017-001742 (Epub ahead of print).
- Stuhlmüller B, Schneider U, González-González JB, Feist E. Disease specific autoantibodies in idiopathic inflammatory myopathies. Front Neurol 2019; 10:438.
