Idiopathic intracranial hypertension (IIH) without papilloedema (IIHWOP)

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Idiopathic intracranial hypertension (IIH) without papilloedema (IIHWOP). This occurs in about 6% of IIH cases. Fully referenced neurology checklist.

Epidemiology

  • This occurs in about 6% of IIH cases

Clinical features

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Cerebrospinal fluid (CSF) analysis

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Magnetic resonance imaging (MRI)

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Treatment

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Synonym

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References

  1. Vieira DSS, Masruha MR, Goncalves AL, et al. Idiopathic intracranial hypertension with and without papilloedema in a consecutive sites of patients with chronic migraine. Cephalalgia 2008; 28:609-613.
  2. Digre KB, Nakamoto BK, Warner JE, Langeberg WJ, Baggaley SK, Katz BJ. A comparison of idiopathic intracranial hypertension with and without papilledema. Headache 2009; 49:185-193.
  3. Labella Alvarez F, Berman G, Lowe M, Kulniwatcharoen P, Mollan SP. Adult idiopathic intracranial hypertension without papilledema: systematic review of literature and future perspectives. J Neuroophthalmol 2026; 46:149-164.
  4. Huff AL, Hupp SL, Rothrock JF. Chronic daily headache with migrainous features due to papilledema-negative idiopathic intracranial hypertension. Cephalalgia 1996; 16:451-452.
  5. Bono F, Messina C, Gilberto C, et al. Bilateral transverse sinus stenosis predicts IIH without papilledema in patients with migraine. Neurology 2006; 67:419-423.

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