Hypokalaemic periodic paralysis: investigations

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Hypokalaemic periodic paralysis: investigations. This is usually low in attacks, Many have normal potassium. Fully referenced neurology checklist.

Serum potassium

  • This is usually low in attacks
  • Many have normal potassium
  • Positive potassium challenge

Muscle biopsy: features

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Electromyogram (EMG): McManis test

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References

  1. Bertorini TE. Neuromuscular Disorders: Treatment and Management. Elsevier Philadelphia 2011 p297-298.
  2. Venance  SL, Cannon SC, Fialho D, et al. The primary periodic paralyses: diagnosis, pathogenesis and treatment. Brain 2006; 129:8-17.
  3. Meola G, Hanna MG, Fontaine B. Diagnosis and new treatment in muscle channelopathies. JNNP 2009; 80: 360-365.
  4. Bertorini TE. Neuromuscular Case Studies. Butterworth Heinemann Philadelphia 2008 p 465-468.
  5. Vivekanandam V, Seutterlin K, Matthews E, et al. Muscle MRI in periodic paralysis shows myopathy is common and correlates with intramuscular fat accumulation. Muscle Nerve 2023 (Online ahead of print).
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