Human herpes virus 6 (HHV-6) infection: clinical presentations

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Human herpes virus 6 (HHV-6) infection: clinical presentations. Solid organ transplantation. Fully referenced neurology checklist.

Encephalitis with other immunocompromised states

  • Solid organ transplantation
  • Conventional immunosuppressive treatments
  • Chimeric antigen receptor (CAR) T-cell therapy
  • Biological immunotherapies

Rhombencephalitis

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Roseola infantum (exanthem subitum, sixth disease)

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Other neurological manifestations

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References

  1. Berzero G, Campanini G, Vegezzi E, et al. Human herpesvirus 6 encephalitis in immunocompetent and immunocompromised hosts. Neurol Neuroimmunol Neuroinflamm 2021; 8:e942.
  2. Berger JR. Learning more about HHV-6 encephalitis. Neurol Neuroimmunol Neuroinflamm 2021 (online ahead of print).
  3. Lautenschlager I, Razonable RR. Human herpesvirus-6 infections in kidney, liver, lung, and heart transplantation: review. Transpl Int 2012; 25:493-502.
  4. Vinnard C, Barton T, Jerud E, Blumberg E. A report of human herpesvirus 6-associated encephalitis in a solid organ transplant recipient and a review of previously published cases. Liver Transpl 2009; 15:1242-1246. 
  5. Yamamoto T, Watarai Y, Goto N, et al. Encephalitis caused by human herpesvirus-6B in pancreas-after-kidney transplantation. Transpl Infect Dis 2014; 16:853-858. 
  6. And 19 more. Subscribe to see the full list

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