Histoplasmosis: management

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Histoplasmosis: management. Serology, H. capsulatum polysaccharide antigen (HPA). Fully referenced neurology checklist.

Blood and urine tests

  • Serology
  • H. capsulatum polysaccharide antigen (HPA)

Cerebrospinal fluid (CSF) analysis

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Biopsy: sites

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Treatment

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References

  1. Wheat J, Myint T, Guo Y, et al. Central nervous system histoplasmosis: multicenter retrospective study on clinical features, diagnostic approach and outcome of treatment. Medicine (Baltimore) 2018; 97:e0245. 
  2. Schwartz S, Kontoyiannis DP, Harrison T, Ruhnke M. Advances in the diagnosis and treatment of fungal infections of the CNS. Lancet Neurol 2018; 17:362-372.
  3. Chakrabarti A. Epidemiology of central nervous system mycoses. Neurol India 2007; 55:191-197. 
  4. Rangel-Castilla L, Hwang SW, White AC, Zhang YJ. Neuroendoscopic diagnosis of central nervous system histoplasmosis with basilar arachnoiditis. World Neurosurg 2012; 77:399.E9-E13.

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