Hippocampal stroke: pathology and causes

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Hippocampal stroke: pathology and causes. Memory processing: verbal and spatial, Learning, Emotions. Fully referenced neurology checklist.

Hippocampal functions

  • Memory processing: verbal and spatial
  • Learning
  • Emotions

Pathology

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Vascular causes

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Substance abuse triggered

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Other causes

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Clinical features

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Unilateral v bilateral hippocampal stroke

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Associated extra-hippocampal features

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Differential diagnosis

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Magnetic resonance imaging (MRI) brain: DWI lesion patterns

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Other investigations

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References

  1. Szabo K, Förster A, Jäger T, et al. Hippocampal lesion patterns in acute posterior cerebral artery stroke: clinical and MRI findings. Stroke 2009; 40:2042-2045. 
  2. Kumral E, Deveci EE, Erdoğan C, Enüstün C. Isolated hippocampal infarcts: vascular and neuropsychological findings. J Neurol Sci 2015; 356:83-89.
  3. Nishiyori Y, Nishida M, Shioda K, Suda S, Kato S. Unilateral hippocampal infarction associated with an attempted suicide: a case report. J Med Case Rep 2014; 8:219. 
  4. Huang D, Lukas RV. Complete bilateral hippocampal diffusion restriction and reversible amnesia following opiate, cocaine, and benzodiazepine abuse. Cureus 2021; 13:e12651. 
  5. Tsai C, O'Reggio A, Mehrabyan A, Williams D, Dujmovic Basuroski I. Bilateral acute hippocampal ischemia in two patients abusing cocaine: what is the outcome? Cureus 2022; 14:e26435. 
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