Henoch Schonlein purpura (HSP): clinical features
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Henoch Schonlein purpura (HSP): clinical features. This is a small vessel non-thrombocytopenic systemic vasculitis. Fully referenced neurology checklist.
Pathology
- This is a small vessel non-thrombocytopenic systemic vasculitis
- There are IgA immune complexes in small venules, capillaries and arterioles
- It has an HLA-DRB1*01 allele predeliction
Diagnostic features
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Gastrointestinal features
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Renal features
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Dermatological features
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Cardiorespiratory features
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Neurological features: central
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Neurological features: peripheral
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Other features
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Differential diagnosis
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Synonym
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References
- Kraft DM, Mckee D, Scott C. Henoch-Schönlein purpura: a review. Am Fam Physician 1998; 58:405-408.
- González-Gay MA, López-Mejías R, Pina T, Blanco R, Castañeda S. IgA vasculitis: genetics and clinical and therapeutic management. Curr Rheumatol Rep 2018; 20:24.
- Chen SY, Kong MS. Gastrointestinal manifestations and complications of Henoch-Schönlein purpura. Chang Gung Med J 2004; 27:175-181.
- Choong CK, Beasley SW. Intra-abdominal manifestations of Henoch-Schönlein purpura. J Paediatr Child Health 1998; 34:405-409.
- Rubino C, Paci M, Resti M, Lionetti P, Trapani S. Late relapse of Henoch-Schönlein purpura in an adolescent presenting as severe gastroduodenitis. Front Pediatr 2018; 6:355.
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