Haematoma expansion: risk factors

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Haematoma expansion: risk factors. Early stroke presentation, Oral anticoagulant use. Fully referenced neurology checklist.

Clinical risk factors

  • Early stroke presentation
  • Oral anticoagulant use
  • High international normalised ratio (INR)
  • Systemic inflammation
  • Elevated D-dimer
  • Reduced platelet activity
  • Apolipoprotein ε2 (APOE2) genotype: this also predicts the Spot sign on CTA

Haematoma risk factors

Locked: subscribe to see this section.

The BAT Score for predicting haematoma expansion

Locked: subscribe to see this section.

References

  1. Goldstein JN, Greenberg SM. Should anticoagulation be resumed after intracerebral hemorrhage? Cleve Clin J Med 2010; 77:791-799.
  2. Moussouttas M. Challenges and controversies in the medical management of primary and antithrombotic-related intracerebral hemorrhage. Ther Adv Neurol Disord 2012; 5:43-56.
  3. Brouwers HB, Chang Y, Falcone GJ, et al. Predicting hematoma expansion after primary intracerebral hemorrhage. JAMA Neurol 2014; 71:158-164.
  4. Flibotte JJ, Hagan N, O'Donnell J, Greenberg SM, Rosand J. Warfarin, hematoma expansion, and outcome of intracerebral hemorrhage. Neurology 2004; 63:1059-1064.
  5. Brouwers HB, Biffi A, Ayres AM, et al. Apolipoprotein E genotype predicts hematoma expansion in lobar intracerebral hemorrhage. Stroke 2012; 43:1490-1495. 
  6. And 4 more. Subscribe to see the full list

Related checklists

Loading...