Guillain Barre syndrome (GBS): predictors of ventilation
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Guillain Barre syndrome (GBS): predictors of ventilation. Older age, Weak cough, Bilateral facial weakness. Fully referenced neurology checklist.
Clinical indications
- Older age
- Weak cough
- Bilateral facial weakness
- Bulbar dysfunction
- Neck flexion weakness
- Generalised severe weakness
- Cranial nerve involvement
- Rapidly progressive course
- Associated dysautonomia
- Underlying pulmonary disease
- Cardiovascular co-morbidities
- Poor values on scoring scales: EGRIS and MRC sum scores
Laboratory indications
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The 20-40-30 rule indication
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Acronyms
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References
- Fish M, Llewelyn G. The Guillain-Barre syndrome. ACNR 2008; 8:10-12.
- Walgaard, C, Lingsma, HF, Ruts, L et al. Prediction of respiratory insufficiency in Guillain-Barré syndrome. Ann Neurol 2010; 67:781–787.
- Oshima Y, Mitsui T, Yoshino H, et al. Central motor conduction in patients with anti-ganglioside antibody associated neuropathy syndromes and hyperreflexia. JNNP 2002; 73:568-573.
- Asbury AK, Cornblath DR. Assessment of current diagnostic criteria for Guillain-Barre syndrome. Ann Neurol 1990; 27(Suppl):S21-S24.
- Lawn ND, Fletcher DD, Henderson RD, Wolter TD, Wijdicks EF. Anticipating mechanical ventilation in Guillain-Barre syndrome. Arch Neurol 2001; 58:893-898.
