Guillain Barre syndrome (GBS): non-infective triggers

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Guillain Barre syndrome (GBS): non-infective triggers. Influenza vaccine: this has the most evidence of risk. Fully referenced neurology checklist.

Vaccination

  • Influenza vaccine: this has the most evidence of risk
  • Rabies vaccine
  • Oral polio vaccine
  • Hepatitis B virus (HBV) vaccine
  • Not tetanus toxoid or mumps measles and rubella (MMR) vaccine

Drug-induced and toxic triggers

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Autoimmune triggers

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Neoplastic triggers

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Miscellaneous triggers

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References

  1. Hughes RAC, Rees JH. Clinical and epidemiologic features of Guillain-Barre syndrome. J Infect Dis 1997; 176(Suppl 2):S92-S98.
  2. Juurlink DN, Stukel TA, Kwong J, et al. Guillain-Barre syndrome after influenza vaccination in adults: a population-based study. Arch Intern Med 2006; 166:2217-2221.
  3. Haber P, DeStefano F, Angulo FJ, et al. Guillain-Barre syndrome following influenza vaccination. JAMA 2004; 292:2478-2481.
  4. Tuttle J, Chen RT, Rantala H, Cherry JD, Rhodes PH, Hadler S. The risk of Guillain-Barre syndrome after tetanus-toxoid-containing vaccines in adults and children in the United States. Am J Public Health 1997; 87:2045-2048.
  5. Patja A, Paunio M, Kinnunen E, Junttila O, Hovi T, Peltola H. Risk of Guillain-Barre syndrome after measles-mumps-rubella vaccination. J Pediatr 2001; 138:250-254.
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