Guillain Barre syndrome (GBS): major types

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Guillain Barre syndrome (GBS): major types. This is typically associated with Campylobacter jejuni. Fully referenced neurology checklist.

Acute motor axial neuropathy (AMAN)

  • This is typically associated with Campylobacter jejuni
  • It is associated anti ganglioside antibodies: anti GM1 and anti GD1a
  • It is more rapidly progressive than demyelinating GBS
  • The reflexes are relatively preserved or increased
  • There is less cranial involvement
  • Autonomic dysfunction is rare
  • It has a longer recovery time

Acute motor and sensory axonal neuropathy (AMSAN)

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Subacute inflammatory demyelinating polyneuropathy

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Sensory GBS

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Pharyngo-cervical-brachial variant

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References

  1. Kuwabara S, Yuki N. Axonal Guillain-Barre syndrome: concepts and controversies. Lancet Neurol 2013; 12:1180-1188.
  2. Oh SJ, Kurokawa K, de Almeida DF, Ryan HF, Claussen GC. Subacute inflammatory demyelinating polyneuropathy. Neurology 2003; 61:1507-1512.
  3. Oh SJ, LaGanke C, Claussen GC. Sensory Guillain Barre syndrome. Neurology 2001; 56:82-86.
  4. Wakerley BR, Yuki N. Pharyngo-cervical-brachial variant of Guillain-Barre syndrome. JNNP 2014; 85:339-344.

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