Germ cell tumours: tumour markers and genetics
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Germ cell tumours: tumour markers and genetics. Endodermal sinus tumours, Mixed germ cell tumours. Fully referenced neurology checklist.
Alpha-fetoprotein (AFP)
- Endodermal sinus tumours
- Mixed germ cell tumours
- Immature teratomas
Beta human chorionic gonadotrophi (beta hCG)
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Placental alkaline phosphatase (PLAP)
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C-KIT
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Genetic mutations
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References
- Echevarría ME, Fangusaro J, Goldman S. Pediatric central nervous system germ cell tumors: a review. Oncologist 2008; 13:690-699.
- Aihara Y, Watanabe S, Amano K, et al. Placental alkaline phosphatase levels in cerebrospinal fluid can have a decisive role in the differential diagnosis of intracranial germ cell tumors. J Neurosurg 2018; doi: 10.3171/2018.3.JNS172520 (Epub ahead of print).
- Kong Z, Wang Y, Dai C, Yao Y, Ma W, Wang Y. Central nervous system germ cell tumors: a review of the literature. J Child Neurol 2018; 33:610-620.
- Dufour C, Guerrini-Rousseau L, Grill J. Central nervous system germ cell tumors: an update. Curr Opin Oncol 2014; 26:622-626.
