Generalised myasthenia gravis (MG)

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Generalised myasthenia gravis (MG). Ptosis, Diplopia, Eyelid myotonia-like phenomenon, Apraxia of eyelid opening. Fully referenced neurology checklist.

Ocular features

  • Ptosis
  • Diplopia
  • Eyelid myotonia-like phenomenon
  • Apraxia of eyelid opening
  • Light sensitivity
  • See Neurochecklist: “Ocular myasthenia gravis”

Bulbopharyngeal features

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Head and neck features

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Head and neck signs

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Limb girdle weakness

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Respiratory muscle weakness

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Chronic fatigue

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Reported non-motor features

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Outcome

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Predictors of good outcome

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Treatment withdrawal

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References

  1. Sieb JP. Myasthenia gravis: an update for the clinician. Clin Exp Immunol 2014; 175:408-418.
  2. Thanvi BR, Lo TCN. Update on myasthenia gravis. Postgrad Med J 2004; 80:690–700.
  3. Jayam Trouth A, Dabi A, Solieman N, Kurukumbi M, Kalyanam J. Myasthenia gravis: a review. Autoimmune Dis 2012; 2012:874680.
  4. Abraham A, Gurevich T, Alcalay RN, Karni A. Myasthenia gravis patients exhibiting an eyelid myotonia-like phenomenon J Neurol Sci 2023; 453:120783.
  5. Naum R, Morena J. Apraxia of eyelid opening in myasthenia gravis. JAMA Neurol 2025; 82:627.
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