Frontotemporal dementia (FTD): differential diagnosis
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Frontotemporal dementia (FTD): differential diagnosis. Primary progressive aphasia (PPA), Vascular dementia. Fully referenced neurology checklist.
Clinical differentials
- Primary progressive aphasia (PPA)
- Vascular dementia
- Alzheimer’s disease (AD)
- Depression
- Frontotemporal brain sagging syndrome (FBSS)
- Cerebrospinal fluid-venous fistula (CSF-venous fistula)
- Primary psychiatric disorders
Differentiating features supporting FTD
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Differentiating features of temporal (tv-FTD) from frontal variant FTD (fv-FTD)
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Differentials of primary progressive aphasia (PPA)
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References
- Rabinovici GD, Miller BL. Frontotemporal lobar degeneration: epidemiology, pathophysiology, diagnosis and management. CNS Drugs 2010; 24:375-398.
- Kertesz A, Nadkarni N, Davidson W, Thomas AW. The Frontal Behavioral Inventory in the differential diagnosis of frontotemporal dementia. J Int Neuropsychol Soc 2000; 6:460-468.
- Mendez MF, Cherrier M, Perryman KM, Pachana N, Miller BL, Cummings JL. Frontotemporal dementia versus Alzheimer's disease: differential cognitive features. Neurology 1996; 47:1189-1194.
- Rosen HJ, Hartikainen KM, Jagust W, et al. Utility of clinical criteria in differentiating Frontotemporal lobar degeneration (FTLD) from AD. Neurology 2002; 58:1608-1615.
- Wicklund MR, Mokri B, Drubach DA, Boeve BF, Parisi JE, Josephs KA. Frontotemporal brain sagging syndrome: an SIH-like presentation mimicking FTD. Neurology 2011; 76:1377-1382.
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