Frontotemporal brain sagging syndrome (FBSS)
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Frontotemporal brain sagging syndrome (FBSS). This is brain sagging secondary to intracranial hypotension. Fully referenced neurology checklist.
Pathology
- This is brain sagging secondary to intracranial hypotension
- It may be spontaneous
- It may follow dural puncture
- It may also result from cerebrospinal fluid-venous fistula (CSF-venous fistula)
Epidemiology
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Behavioural features
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Bulbar features
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Other features
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Differential diagnosis
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Magnetic resonance imaging (MRI) brain: features
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Cerebrospinal fluid (CSF) analysis
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Electroencephalogram (EEG)
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Positron emission tomography (PET) scan
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Treatment
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Synonym
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References
- Wicklund MR, Mokri B, Drubach DA, Boeve BF, Parisi JE, Josephs KA. Frontotemporal brain sagging syndrome: an SIH-like presentation mimicking FTD. Neurology 2011; 76:1377-1382.
- Slattery CF, Malone IB, Clegg SL, Warren JD, Fox NC. Reversible frontotemporal brain sagging syndrome. Neurology 2015; 85:833.
- Schievink WI, Maya M, Barnard Z, et al. The reversible impairment of behavioral variant frontotemporal brain sagging syndrome: Challenges and opportunities. Alzheimers Dement (N Y) 2022; 8:e12367.
- Ortega-Porcayo LA, Ortega EP, Quiroz-Castro O, et al. Frontotemporal brain sagging syndrome: craniospinal hypovolemia secondary to a T6-T7 cerebrospinal fluid-venous fistula. Surg Neurol Int 2020; 11:250.
- Lashkarivand A, Eide PK. Brain sagging dementia-diagnosis, treatment, and outcome: a review. Neurology 2022; 98:798-805.
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