Folate deficiency syndromes: classification
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Folate deficiency syndromes: classification. Stroke, Cerebral folate deficiency (CFD), Encephalopathy, Mood disorder. Fully referenced neurology checklist.
Central folate deficiency syndromes
- Stroke
- Cerebral folate deficiency (CFD)
- Encephalopathy
- Mood disorder
- Psychosis
Spinal folate deficiency syndromes
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Peripheral folate deficiency syndromes
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References
- Manzoor M, Runcie J. Folate-responsive neuropathy: report of 10 cases. Br Med J 1976; 1:1176-1178.
- Zhao M, Wu G, Li Y, Wang X, Hou FF, Xu X, Qin X, Cai Y. Meta-analysis of folic acid efficacy trials in stroke prevention: Insight into effect modifiers. Neurology 2017; 88:1830-1838.
- Zeng R, Xu CH, Xu YN, Wang YL, Wang M. The effect of folate fortification on folic acid-based homocysteine-lowering intervention and stroke risk: a meta-analysis. Public Health Nutr 2015; 18:1514-1521.
- Qin X, Li J, Spence JD, Zhang Y, et al. Folic acid therapy reduces the first stroke risk associated with hypercholesterolemia among hypertensive patients. Stroke 2016; 47:2805-2812.
- Huo Y, Li J, Qin X, et al; CSPPT Investigators. Efficacy of folic acid therapy in primary prevention of stroke among adults with hypertension in China: the CSPPT randomized clinical trial. JAMA 2015; 313:1325-1335.
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