Eslicarbazepine: clinical use

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Eslicarbazepine: clinical use. Eslicarbazepine is a third generation dibenzazepine. Fully referenced neurology checklist.

Mode of action

  • Eslicarbazepine is a third generation dibenzazepine
  • It blocks voltage-gated sodium channels (VGSC)

Dosing

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Indications

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Systemic side effects

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Neurological side effects

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Drugs whose blood levels are reduced by Esclicarbazepine

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Drugs which reduce Esclicarbazepine blood levels

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References

  1. Rocamora R. A review of the efficacy and safety of eslicarbazepine acetate in the management of partial-onset seizures. Ther Adv Neurol Disord 2015; 8:178-186. 
  2. Shirley M, Dhillon S. Eslicarbazepine Acetate Monotherapy: A Review in Partial-Onset Seizures. Drugs 2016; 76:707-717. 
  3. Tambucci R, Basti C, Maresca M, Coppola G, Verrotti A. Update on the role of eslicarbazepine acetate in the treatment of partial-onset epilepsy. Neuropsychiatr Dis Treat 2016; 12:1251-1260. 
  4. Chaves J, Breia P, Pimentel J, et al. Eslicarbazepine acetate as adjunctive therapy in clinical practice: ESLADOBA study. Acta Neurol Scand 2017; 264:421-431.
  5. Galiana GL, Gauthier AC, Mattson RH. Eslicarbazepine acetate: a new improvement on a classic drug family for the treatment of partial-onset seizures. Drugs R D 2017; 17:329-339. 
  6. And 2 more. Subscribe to see the full list

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