Epileptic encephalopathy with electrical status epilepticus in sleep (ESES): treatment

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Epileptic encephalopathy with electrical status epilepticus in sleep (ESES): treatment. Steroids. Fully referenced neurology checklist.

Immunotherapy

  • Steroids
  • Intravenous immunoglobulins (IVIg)
  • ACTH

Antiepileptic drugs (AEDs)

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Potentially beneficial drugs

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Surgery

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Other treatments

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Predictors of treatment response

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Synonyms

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References

  1. van den Munckhof B, van Dee V, Sagi L, et al. Treatment of electrical status epilepticus in sleep: a pooled analysis of 575 cases. Epilepsia 2015; 56:1738-1746.
  2. Veggiotti P, Pera MC, Teutonico F, Brazzo D, Balottin U, Tassinari CA. Therapy of encephalopathy with status epilepticus during sleep (ESES/CSWS syndrome): an update. Epileptic Disord 2012; 14:1-11.
  3. Buzatu M, Bulteau C, Altuzarra C, Dulac O, Van Bogaert P. Corticosteroids as treatment of epileptic syndromes with continuous spike-waves during slow-wave sleep. Epilepsia 2009; 50(Suppl 7):68-72.
  4. Sinclair DB, Snyder TJ. Corticosteroids for the treatment of Landau-kleffner syndrome and continuous spike-wave discharge during sleep. Pediatr Neurol 2005; 32:300-306.
  5. Chen J, Yang Z, Liu X, et al. Efficacy of methylprednisolone therapy for electrical status epilepticus during sleep in children. Zhonghua Er Ke Za Zhi 2014; 52:678-682.
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