Epilepsy: risk factors for relapse after treatment withdrawal
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Epilepsy: risk factors for relapse after treatment withdrawal. Young age at onset of epilepsy, Female sex. Fully referenced neurology checklist.
Subject-related risk factors
- Young age at onset of epilepsy
- Female sex
- Developmental delay
- Family history of epilepsy
Seizure-related risk factors
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Anti-epileptic drug (AED) related risk factors
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Non-risk factors
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References
- Lamberink HJ, Otte WM, Geerts AT, et al. Individualised prediction model of seizure recurrence and long-term outcomes after withdrawal of antiepileptic drugs in seizure-free patients: a systematic review and individual participant data meta-analysis. Lancet Neurol 2017; 16:523-531.
- Kwan P, Sander JW. The natural history of epilepsy: an epidemiological view. JNNP 2004; 75:1376-1381.
- Tang X, Yu P, Ding D, et al. Risk factors for seizure reoccurrence after withdrawal from antiepileptic drugs in individuals who have been seizure-free for over 2 years. PLoS One 2017; 12:e0181710.
- Su L, Di Q, Yu N, Zhang Y. Predictors for relapse after antiepileptic drug withdrawal in seizure-free patients with epilepsy. J Clin Neurosci 2013; 20:790-794.
