Epilepsy and the heart

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Epilepsy and the heart. This develops when seizures disrupt the normal cardiac rhythm. Fully referenced neurology checklist.

Ictal bradycardia syndrome

  • This develops when seizures disrupt the normal cardiac rhythm
  • It usually affects men older than 50 years: a quarter are older than 60 years
  • Temporal lobe epilepsy (TLE) accounts for >80% of cases
  • A pacemaker is indicated when epilepsy manifests with refractory syncope

Ictal asystole

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References

  1. Reeves AL, Nollet KE, Klass DW, Sharbrough FW, So EL. The ictal bradycardia syndrome. Epilepsia 1996; 37:983-987.
  2. Tinuper P, Bisulli F, Cerullo A, et al. Ictal bradycardia in partial epileptic seizures. Brain 2001; 124:2361-2371.
  3. Bergfeldt L. Differential diagnosis of cardiogenic syncope and seizure disorders. Heart 2003; 89:353-358.
  4. Schuele SU, Bermeo AC, Alexopoulos AV, et al. Video-electrographic and clinical features in patients with ictal asystole. Neurology 2007; 69:434.
  5. So NK, Sperling MR. Ictal asystole and SUDEP. Neurology 2007; 69:423.

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