Effects of myasthenia gravis on pregnancy
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Effects of myasthenia gravis on pregnancy. Pregnancy does not generally worsen MG. Fully referenced neurology checklist.
The effect of pregnancy on MG
- Good pre-pregnancy symptom control is usually maintained in pregnancy
- Pregnancy does not generally worsen MG
- Symptoms may improve during pregnancy
- Symptoms may worsen in the 12-month post-partum period
Adverse effects of MG on pregnancy
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Neutral effects of MG on pregnancy
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Adverse effects of MG on the foetus
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References
- Norwood F, Dhanjal M, Hill M, et al. Myasthenia in pregnancy: best practice guidelines from a UK multispecialty writing group. JNNP 2014; 85:538-543.
- Tellez-Zenteno JF, Hernandez-Ronquillo L, Salinas V, Estanol B, da Silva O. Myasthenia gravis and pregnancy: clinical implications and neonatal outcome. BMC Musculoskelet Disord 2004; 5:42.
- Skeie GO, Apostolski S, Evoli A, et al. Guidelines for treatment of autoimmune neuromuscular transmission disorders. Eur J Neurol 2010; 17:893-902.
- Hoff JM, Daltveit AK, Gilhus N. Myasthenia gravis: consequences for pregnancy, delivery and the newborn. Neurology 2003; 61:1459-1460.
- O'Connor L, Gabrysch K, Wikström AK, Rostedt Punga A. Risk of myasthenia gravis exacerbation during pregnancy and postpartum: a nationwide cohort study. Neurology 2026; 106:e218082.
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