Dravet syndrome: clinical features
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Dravet syndrome: clinical features. This is an infantile onset epileptic encephalopathy. Fully referenced neurology checklist.
Epidemiology
- This is an infantile onset epileptic encephalopathy
- It causes severe myoclonic epilepsy of infancy
- There is a family history of epilepsy in 25% of cases
- Pertussis vaccination may provoke an earlier onset by causing fever
Types
Locked: subscribe to see this section.
Onset features
Locked: subscribe to see this section.
Developmental features
Locked: subscribe to see this section.
Speech and language impairments
Locked: subscribe to see this section.
Seizure types
Locked: subscribe to see this section.
Seizure features
Locked: subscribe to see this section.
Sleep disorders
Locked: subscribe to see this section.
Other features
Locked: subscribe to see this section.
Dravet syndrome in adulthood
Locked: subscribe to see this section.
Acronym
Locked: subscribe to see this section.
References
- Millichap JJ, Koh S, Laux LC, Nordli DR. Dravet syndrome: when to suspect the diagnosis. Neurology 2009; 73:e59-e62.
- van Dam VS, Korff CM. Dravet syndrome: an update. Schweiz Arch Neurol Psychiatr 2013; 164:153-157.
- Dravet C. The core Dravet syndrome. Epilepsia 2011; 52(Suppl 2): 3-9.
- Carvill GL, Weckchuysen S, McMahon JM, et al. GABRA1 and STXBP1: novel genetic causes of Dravet syndrome. Neurology 2014; 82:1245-1253.
- Cetica V, Chiari S, Mei D, et al. Clinical and genetic factors predicting Dravet syndrome in infants with SCN1A mutations. Neurology 2017; 88:1037-1044.
- And 12 more. Subscribe to see the full list
