Dopamine dysregulation syndrome (DDS)
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Dopamine dysregulation syndrome (DDS). Compulsive drug consumption, Agitation, Euphoria, Dyskinesias. Fully referenced neurology checklist.
Clinical features
- Compulsive drug consumption
- Agitation
- Euphoria
- Dyskinesias
- Resistance to drug withdrawal
- Excessive shopping
- Compulsive eating
- Hypersexuality
- Gambling
- Aggression
- Social isolation
Risk factors
Locked: subscribe to see this section.
Treatment
Locked: subscribe to see this section.
Outcome
Locked: subscribe to see this section.
References
- Cilia R, Siri C, Canesi M, et al. Dopamine dysregulation syndrome in Parkinson's disease: from clinical and neuropsychological characterisation to management and long-term outcome. JNNP 2014; 85:311-318.
- Merims D, Giladi N. Dopamine dysregulation syndrome, addiction, and behavioural changes in Parkinson’s disease. Parkinsonism Relat Disord 2008; 14:273-280.
- Pondal M, Marras C, Miyasaki J, et al. Clinical features of dopamine agonist withdrawal syndrome in a movement disorder clinic. JNNP 2013; 84:130-135.
