Disease modifying treatments (DMTs): classification
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Disease modifying treatments (DMTs): classification. Interferon β 1a, Interferon β 1b. Fully referenced neurology checklist.
Interferons
- Interferon β 1a
- Interferon β 1b
- Pegylated interferon (PEG interferon) β-1a
Monoclonal antibodies
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Oral agents
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Other agents
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Conventional first line DMTs for MS
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First line DMTs for aggressive disease
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Second line DMTs for aggressive disease
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Newer DMTs
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References
- Torkildsen Ø, Myhr KM, Bø L. Disease-modifying treatments for multiple sclerosis-a review of approved medications. Eur J Neurol 2016; 23(Suppl 1):18-27.
- Castro-Borrero W, Graves D, Frohman TC, et al. Current and emerging therapies in multiple sclerosis: a systematic review. Ther Adv Neurol Disord 2012; 5:205-220.
- Dargahi N, Katsara M, Tselios T, et al. Multiple sclerosis: immunopathology and treatment update. Brain Sci 2017; 7(7) pii: E78.
- Rejdak K, Jackson S, Giovannoni G. Multiple sclerosis: a practical overview for clinicians. Br Med Bull 2010; 95:79-104.
- Rice CM. Disease modification in multiple sclerosis: an update. Pract Neurol 2014; 14:6-13.
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