Dialysis dementia: clinical features
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Dialysis dementia: clinical features. This is cognitive impairment arising during long-term dialysis. Fully referenced neurology checklist.
Background
- This is cognitive impairment arising during long-term dialysis
- It is most likely caused by aluminium toxicity
- It can be triggered by deferoxamine treatment of aluminium-related bone diseae
- It usually develops 14-36 months after the start of dialysis
Language features
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Cognitive features
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Movement disorders
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Psychiatric features
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Other features
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Differential diagnosis: metabolic encephalopathies
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Differential diagnosis: others
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Synonym
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References
- Chen Y, Tian X, Wang X. Advances in dialysis encephalopathy research: a review. Neurol Sci 2018; 39:1151-1159.
- Sprague SM, Corwin HL, Wilson RS, Mayor GH, Tanner CM. Encephalopathy in chronic renal failure responsive to deferoxamine therapy. another manifestation of aluminum neurotoxicity. Arch Intern Med 1986; 146:2063-2064.
- Burks JS, Alfrey AC, Huddlestone J, Norenberg MD, Lewin E. A fatal encephalopathy in chronic haemodialysis patients. Lancet 1976; 1:764-768.
- Mach JR Jr, Korchik WP, Mahowald MW. Dialysis dementia. Clin Geriatr Med 1988; 4:853-867.
- Sherrard DJ, Walker JV, Boykin JL. Precipitation of dialysis dementia by deferoxamine treatment of aluminum-related bone disease. Am J Kidney Dis 1988; 12:126-130.
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