Dengue virus infection (DENV): management

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Dengue virus infection (DENV): management. Serology using IgM capture (MAC)-ELISA: for Dengue virus-specific IgM antibodies.

Viral studies

  • Serology using IgM capture (MAC)-ELISA: for Dengue virus-specific IgM antibodies
  • Viral detection with viral cell culture: NS1 antigen or RNA by RT-PCR

Cerebrospinal fluid (CSF) analysis: features

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Electroencephalogram (EEG): features

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Magnetic resonance imaging (MRI) brain: features

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Magnetic resonance imaging (MRI) spinal cord: features

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Other investigations

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Treatment

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Poor prognostic features

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Acronym

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References

  1. Carod-Artal FJ, Wichmann O, Farrar J, Gascón J. Neurological complications of dengue virus infection. Lancet Neurol 2013; 12:906-919. 
  2. Verma R, Sahu R, Holla V. Neurological manifestations of dengue infection: a review. J Neurol Sci 2014; 346:26-34. 
  3. Li GH, Ning ZJ, Liu YM, Li XH. Neurological manifestations of dengue infection. Front Cell Infect Microbiol 2017; 7:449.  
  4. Misra UK, Kalita J, Syam UK, Dhole TN. Neurological manifestations of dengue virus infection. J Neurol Sci 2006; 244:117-122. 
  5. Wasay M, Channa R, Jumani M, Shabbir G, Azeemuddin M, Zafar A. Encephalitis and myelitis associated with dengue viral infection clinical and neuroimaging features. Clin Neurol Neurosurg 2008; 110:635-640. 
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