Cyclic seizures

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Cyclic seizures. These are non-convulsive seizures usually seen in critically ill people. Fully referenced neurology checklist.

Pathology

  • These are non-convulsive seizures usually seen in critically ill people
  • They recur at regular intervals at least three times an hour
  • They result from the failure of physiological seizure-terminating mechanisms
  • They are usually focal onset and posterior
  • They may progress to status epilepticus
  • A cyclic and diurnal pattern is also seen in most other seizures

Cyclic patterns

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Risk factors

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Cardiorespiratory features

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Continuous electroencephalogram (EEG)

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Treatment

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Synonym

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References

  1. Hammer D, Scheuer M, Fong-Isariyawongse J. Pearls & Oy-sters: Cyclic seizures and heart rate variability. Neurology 2021; 96:e1694-e1696.
  2. Pinto LF, Gilmore EJ, Petroff OA, et al. Cyclic seizures in critically ill patients: Clinical correlates, DC recordings and outcomes. Clin Neurophysiol 2017; 128:1083-1090.
  3. Friedman DE, Schevon C, Emerson RG, Hirsch LJ. Cyclic electrographic seizures in critically ill patients. Epilepsia 2008; 49:281-287.
  4. Zorlu MM, Chuang DT, Buyukozkan M, Aydemir S, Zarnegar R. Prognostic significance of cyclic seizures in status epilepticus. J Clin Neurophysiol 2021; 38:516-524.
  5. Karoly PJ, Goldenholz DM, Freestone DR, et al. Circadian and circaseptan rhythms in human epilepsy: a retrospective cohort study. Lancet Neurol 2018; 17:977-985.
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