Curranino syndrome
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Curranino syndrome. This is caused by mutations in the MNX1 (HLXB9) gene. Fully referenced neurology checklist.
Genetics and pathology
- This is caused by mutations in the MNX1 (HLXB9) gene
- The mutations result in an abnormal separation of the neuroectoderm and endoderm
Clinical triad
Locked: subscribe to see this section.
Associated features
Locked: subscribe to see this section.
Differential diagnosis
Locked: subscribe to see this section.
Investigations
Locked: subscribe to see this section.
Surgical treatments
Locked: subscribe to see this section.
References
- Verma A, Attry S, Haldenia K, Gupta VK, Bansal P. Currarino syndrome presenting in adulthood: a rare case. Cureus 2023; 15:e36497.
- Kole MJ, Fridley JS, Jea A, Bollo RJ. Currarino syndrome and spinal dysraphism. J Neurosurg Pediatr 2014; 13:685-689.
- Crétolle C, Sarnacki S, Amiel J, et al. Currarino syndrome shown by prenatal onset ventriculomegaly and spinal dysraphism Am J Med Genet A 2007; 143A:871-874.
- Duru S, Karabagli H, Turkoglu E, Erşahin Y. Currarino syndrome: report of five consecutive patients. Childs Nerv Syst 2014; 30:547-552.
- Emans PJ, van Aalst J, van Heurn EL, et al. The Currarino triad: neurosurgical considerations. Neurosurgery 2006; 58:924-929.
