Cryptococcal meningitis: clinical features
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Cryptococcal meningitis: clinical features. This is caused by Cryptococcus neoformans and gatti. Fully referenced neurology checklist.
Pathology
- This is caused by Cryptococcus neoformans and gatti
- It is acquired by inhalation
- It resides in lymph nodes
- It disseminates after a latent period
- It has a predilection for the nervous system
- It causes a subacute meningoencephalitis
Risk factors: cell-mediated immunodeficiency syndromes
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Risk factors: others
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Neurological features
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Ophthalmic features
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Systemic features
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Cryptococcal immune reconstitution inflammatory syndrome (IRIS)
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Cryptococcal meningitis associated disorders
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Outcome
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Synonym
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References
- Williamson PR, Jarvis JN, Panackal AA, et al. Cryptococcal meningitis: epidemiology, immunology, diagnosis and therapy. Nat Rev Neurol 2017; 13:13-24.
- Celis-Aguilar E, Macias-Valle L, Coutinho-De Toledo H. Auditory neuropathy secondary to cryptococcal central nervous system infection in 2 immunocompromised patients. Otolaryngol Head Neck Surg 2012; 147:597-598.
- Wang HC, Chang WN, Lui CC, et al. The prognosis of hearing impairment complicating HIV-negative cryptococcal meningitis. Neurology 2005; 65:320-322.
- Mishra AK, Arvind VH, Muliyil D, et al. Cerebrovascular injury in cryptococcal meningitis. Int J Stroke 2018; 13:57-65.
- Mishra AK, Vanjare HA, Raj PM. Cryptococcal meningitis presenting as acute onset bilateral cerebellar infarct. J Neurosci Rural Pract 2017; 8:159-160.
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