Critical illness neuropathy (CIN)
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Critical illness neuropathy (CIN). Sepsis, Systemic inflammatory response syndrome (SIRS), Multiorgan failure. Fully referenced neurology checklist.
Risk factors
- Sepsis
- Systemic inflammatory response syndrome (SIRS)
- Multiorgan failure
- Severity of illness
- Duration of intensive therapy unit (ITU) stay
- Hyperglycaemia
- Renal failure
- Hyperosmolality
- Parenteral nutrition
Pathology
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Clinical features
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Differential diagnosis
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Treatment
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Prognosis
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References
- Latronico N, Bolton CF. Critical illness polyneuropathy and myopathy: a major cause of muscle weakness and paralysis. Lancet Neurol 2011; 10:931-941.
- De Letter MACJ, Visser LH, Ang W, van Der Meche FGA, Savelkoul HF. Distinctions between critical illness polyneuropathy and axonal Guillain-Barre syndrome. JNNP 2000; 68:397-398.
- Guarneri B, Bertolini G, Latronico N. Long-term outcome in patients with critical illness myopathy or neuropathy: the Italian multicentre CRIMYNE study. JNNP 2008; 79:838-841.
- Koch S, Spuler S, Deja M, et al. Critical illness myopathy is frequent: accompanying neuropathy protracts ICU discharge. JNNP 2011; 82:287-293.
