Corpus callosum lesions: causes
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Corpus callosum lesions: causes. The lesions are on the inner callosal surface. They are well-demarcated. Fully referenced neurology checklist.
Multiple sclerosis (MS)
- The lesions are on the inner callosal surface
- They are well-demarcated
- They show the subcallosal dot-dash sign more often than NMO
Neuromyelitis optica (NMO)
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Acute disseminated encephalomyelitis (ADEM)
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Susac’s syndrome
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Other demyelinating disorders
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Hypoxic ischaemic causes
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Vasculitis
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Other vascular disorders
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Infective causes
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Malignant causes
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Toxic causes
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Leukodystrophies
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Mild encephalopathy with reversible splenial lesions (MERS)
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Other causes
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References
- Renard D, Castelnovo G, Campello C, et al. An MRI review of acquired corpus callosum lesions. JNNP 2014; 85:1041-1048.
- Bhidayasiri R, Waters MF, Giza CC. Neurological Differential Diagnosis: A Prioritized Approach. Blackwell Publishing Massachusetts 2005 p422.
- Grossman RI, Yousem DM. The requisites Neuroradiology. 2nd edition Mosby Philadelphia 2003 p145.
- Garg N, Reddel SW, Miller DH, et al. The corpus callosum in the diagnosis of multiple sclerosis and other CNS demyelinating and inflammatory diseases. JNNP 2015; 86:1374-1382.
- Saied Z, Rachdi A, Jeridi C, et al. Corpus callosum lesion as the main clinical and radiological expression of Neurobehçet: a case report. Rev Neurol (Paris) 2022; 178:403-404.
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