Convulsive status epilepticus: prognostic features
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Convulsive status epilepticus: prognostic features. Older age: ≥65 years, Potentially fatal aetiologies. Fully referenced neurology checklist.
Clinical predictors of poor prognosis
- Older age: ≥65 years
- Potentially fatal aetiologies
- De novo onset in hospitalised patients
- Impairment of consciousness
- Prolonged seizure duration
- Focal neurological signs at onset
- Medical complications
- Inadequate Benzodiazepine dosing
Investigative predictors of poor prognosis
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Risk factors for recurrent status epilepticus
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Outcome prediction scales
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References
- Brophy GM, Bell R, Claassen J, et al. Guidelines for the evaluation and management of status epilepticus. Neurocrit Care 2012; 17:3-23.
- Atmaca MM, Bebek N, Baykan B, Gökyiğit A, Gürses C. Predictors of outcomes and refractoriness in status epilepticus: A prospective study. Epilepsy Behav 2017; 75:158-164.
- Rao SK, Mahulikar A, Ibrahim M, Shah A, Seraji-Bozorgzad N, Mohamed W. Inadequate benzodiazepine dosing may result in progression to refractory and non-convulsive status epilepticus. Epileptic Disord 2018; 20:265-269.
- Nass RD, Motloch LJ, Paar V, et al. Blood markers of cardiac stress after generalized convulsive seizures. Epilepsia 2019; 60:201-210.
- Bonduelle T, Ollivier M, Trin K, et al. Association of peri-ictal MRI abnormalities with mortality, antiseizure medication refractoriness, and morbidity in status epilepticus. Neurology 2023; 100:e943-e953.
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