Complex regional pain syndrome (CRPS): clinical features

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Complex regional pain syndrome (CRPS): clinical features. Acutely painful, red, and swollen limb, Allodynia. Fully referenced neurology checklist.

Pain features

  • Acutely painful, red, and swollen limb
  • Allodynia
  • Hyperpathia
  • Proximal but not distal spread of symptoms

Motor features

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Movement disorders

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Autonomic features

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Other features

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Co-morbidities

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Differential diagnosis

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References

  1. Marinus J, Moseley GL, Birklein F. Clinical features and pathophysiology of complex regional pain syndrome. Lancet Neurol 2011; 10:637-648.
  2. Turner-Stokes L, Goebel A. Complex regional pain syndrome in adults: concise guidance. Clin Med 2011; 11:596-600.
  3. Goebel A. Complex regional pain syndrome in adults. Rheumatology (Oxford) 2011; 50:1739-1750.
  4. Schott GD. Complex? Regional? Pain? Syndrome? Pract Neurol 2007; 7:145-157.
  5. Peterlin BL, Rosso AL, Nair S, Young WB, Schwartzman RJ. Migraine may be a risk factor for the development of complex regional pain syndrome. Cephalalgia 2010; 30:214-223.
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