Cluster headache (CH): transitional prophylaxis
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Cluster headache (CH): transitional prophylaxis. The dose is 60mg daily for 5 days. Fully referenced neurology checklist.
Prednisolone
- The dose is 60mg daily for 5 days
- Alternatively, 100 mg daily for 5 days
Suboccipital steroid injection
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Methysergide
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Ergotamine tartrate
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Dihydroergotamine
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Frovatriptan
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References
- Nesbitt AD, Goadsby PJ. Cluster headache. BMJ 2012; 344:e2407.
- Ashkenazi A, Schwedt T. Cluster headache-acute and prophylactic therapy. Headache 2011; 51:272-286.
- Matharu M, Goadsby P. Cluster headache. Pract Neurol 2001; 1:42-49.
- Francis GJ, Becker WJ, Pringsheim TM. Acute and preventive pharmacologic treatment of cluster headache. Neurology 2010; 75:463-473.
- Obermann M, Nägel S, Ose C, et al. Safety and efficacy of prednisone versus placebo in short-term prevention of episodic cluster headache: a multicentre, double-blind, randomised controlled trial. Lancet Neurol 2021; 20:29-37.
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Related checklists
- Cluster headache (CH): causes
- Cluster headache (CH): triggers and red flags
- Cluster headache (CH): clinical features
- Cluster headache (CH): co-morbid disorders
- Cluster headache (CH) in women
- Cluster headache (CH): acute treatment
- Cluster headache (CH): chronic drug prophylaxis
- Cluster headache (CH): interventional prophylaxis
