CLIPPERS: treatment
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
CLIPPERS: treatment. Steroid responsiveness is not universal, Symptoms may relapse on steroid tapering. Fully referenced neurology checklist.
Steroid treatment
- Steroid responsiveness is not universal
- Symptoms may relapse on steroid tapering
Steroid-sparing immunosuppression: conventional types
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Steroid-sparing immunosuppression: case reports
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Acronym
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References
- Taieb G, Allou T, Labauge P. Therapeutic approaches in CLIPPERS. Curr Treat Options Neurol 2017; 19:17.
- Tobin WO, Guo Y, Krecke KN, et al. Diagnostic criteria for chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS). Brain 2017; 140:2415-2425.
- Rico M, Villafani J, Tuñón A, Mateos V, Oliva-Nacarino P. IFN beta 1a as glucocorticoids-sparing therapy in a patient with CLIPPERS. Am J Case Rep 2016; 17:47-50.
- Cipriani VP, Arndt N, Pytel P, Reder AT, Javed A. Effective treatment of CLIPPERS with long-term use of rituximab. Neurol Neuroimmunol Neuroinflamm 2018; 5:e448.
- Rempe T, Becktepe JS, Metz I, et al. A case of CLIPPERS syndrome responsive to tocilizumab. Neurol Neuroimmunol Neuroinflamm 2019; 6:e545.
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