CIDP associated with nodal and paranodal antibodies
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
CIDP associated with nodal and paranodal antibodies. Neurofascin 155 (NF155), Neurofascin 186, Neurofascin 140. Fully referenced neurology checklist.
Neurofascin antibodies
- Neurofascin 155 (NF155)
- Neurofascin 186
- Neurofascin 140
- Also see Neurochecklist: CIDP with anti-neurofascin antibodies”
Contactin (CNTN1)
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Contactin-associated protein 1 (Caspr)
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Other antibodies
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Antibodies with conflicting reports: DLAT
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References
- Kuwahara M, Suzuki H, Oka N, et al. Electron microscopic abnormality and therapeutic efficacy in chronic inflammatory demyelinating polyneuropathy with anti-neurofascin155 immunoglobulin G4 antibody. Muscle Nerve 2017; doi: 10.1002/mus.25757 (Epub ahead of print).
- Devaux JJ, Miura Y, Fukami Y, Inoue T, Manso C, Belghazi M, Sekiguchi K, Kokubun N, Ichikawa H, Wong AH, Yuki N. Neurofascin-155 IgG4 in chronic inflammatory demyelinating polyneuropathy. Neurology 2016; 86:800-807.
- Querol L, Rojas-García R, Diaz-Manera J, et al. Rituximab in treatment-resistant CIDP with antibodies against paranodal proteins. Neurol Neuroimmunol Neuroinflamm 2015; 2:e149.
- Koike H, Kadoya M, Kaida KI, et al. Paranodal dissection in chronic inflammatory demyelinating polyneuropathy with anti-neurofascin-155 and anti-contactin-1 antibodies. JNNP 2017; 88:465-473.
- Doppler K, Appeltshauser L, Villmann C, et al. Auto-antibodies to contactin-associated protein 1 (Caspr) in two patients with painful inflammatory neuropathy. Brain 2016; 139:2617-2630.
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