Cervical artery dissection (CAD): causes and risk factors

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Cervical artery dissection (CAD): causes and risk factors. Male gender, Older age, Low body weight. Fully referenced neurology checklist.

Demographic risk factors

  • Male gender
  • Older age
  • Low body weight
  • Family history of vascular disease

Metabolic risk factors

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Vascular risk factors

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Infective risk factors

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Environmental risk factors

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Direct causes

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Other causes

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Familial CAD (fCAD): genetic variants

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Familial CAD (fCAD): suggestive variants

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References

  1. Debette S, Leys D. Cervical-artery dissections: predisposing factors, diagnosis, and outcome. Lancet Neurol 2009; 8:668-678.
  2. Rubinstein SM, Peerdeman SM, van Tulder MW, Riphagen I, Haldeman S. A systematic review of the risk factors for cervical artery dissection. Stroke 2005; 36:1575-1580.
  3. Debette S, Markus H. The genetics of cervical artery dissection: a systematic review. Stroke 2009; 40:e459-e466.
  4. Arnold M, Kappeler L, Georgiadis D, et al. Gender differences in spontaneous cervical artery dissection. Neurology 2006; 67: 1050-1052.
  5. Metso AJ, Metso TM, Debette S, et al. Gender and cervical artery dissection. Eur J Neurol 2012; 19:594-602.
  6. And 37 more. Subscribe to see the full list

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