Cerebral cavernous malformations (cavernomas): surgical excision

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Cerebral cavernous malformations (cavernomas): surgical excision. Superficial lesions, Overt bleeding. Fully referenced neurology checklist.

Indications

  • Superficial lesions
  • Overt bleeding
  • Accessible non-eloquent areas
  • Progressive enlargement with mass effect
  • Accessible single lesion with seizures: especially temporal lobe

Indications for asymptomatic brain lesions

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Indications for symptomatic brain lesions

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Indications for brainstem lesions

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Indications for spinal lesions

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Surgical resection (microsurgery) of spinal cavernomas

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References

  1. Akers AL, Albanese J, Alcazar-Felix RJ, et al. Guidelines for the diagnosis and clinical management of cavernous malformations of the brain and spinal cord: consensus recommendations based on a systematic literature review by the Alliance to Cure Cavernous Malformation Clinical Advisory Board Experts Panel. Neurosurgery 2026; 98:3-22.
  2. Akers A, Al-Shahi Salman R, A Awad I, et al. Synopsis of guidelines for the clinical management of cerebral cavernous malformations: consensus recommendations based on systematic literature review by the Angioma Alliance Scientific Advisory Board Clinical Experts Panel. Neurosurgery 2017; 80:665-680.
  3. Bian LG, Bertalanffy H, Sun QF, Shen JK. Intramedullary cavernous malformations: clinical features and surgical technique via hemilaminectomy. Clin Neurol Neurosurg 2009; 111:511-517. 
  4. Reitz M, Burkhardt T, Vettorazzi E, et al. Intramedullary spinal cavernoma: clinical presentation, microsurgical approach, and long-term outcome in a cohort of 48 patients. Neurosurg Focus 2015; 39:E19. 
  5. Labauge P, Bouly S, Parker F, et al; French Study Group of Spinal Cord Cavernomas. Outcome in 53 patients with spinal cord cavernomas. Surg Neurol 2008; 70:176-181.
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