Calf hypertrophy: causes

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Calf hypertrophy: causes. LGMD 1C, LGMD 2I, LGMD 2T, LGMD 2C, LGMD 2E, LGMD 2G, LGMD 2U. Fully referenced neurology checklist.

Limb girdle muscular dystrophy (LGMD)

  • LGMD 1C
  • LGMD 2I
  • LGMD 2T
  • LGMD 2C
  • LGMD 2E
  • LGMD 2G
  • LGMD 2U

Congenital myopathies

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Other muscular dystrophies

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Other myopathies

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Nerve disorders

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Systemic causes

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Causes of relative calf hypertrophy

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References

  1. Reimers CD, Schlotter B, Eicke BM, Witt TN. Calf enlargement in neuromuscular diseases: a quantitative ultrasound study in 350 patients and review of the literature. J Neurol Sci 1996; 143:46-56.
  2. Kottlors M, Mueller K, Kirschner J, Glocker FX. Muscle hypertrophy of the lower leg caused by L5 Radiculopathy. J Bone Spine 2009; 76:562-564.
  3. Amato AA, Russell JA. Neuromuscular disorders. McGraw Hill New York 2008 p546.
  4. Oestergaard ST, Stojkovic T, Dahlqvist JR, et al. Muscle involvement in limb-girdle muscular dystrophy with GMPPB deficiency (LGMD2T). Neurol Genet 2016; 2:e112.
  5. Al-Zaidy SA, Malik V, Kneile K, et al. A slowly progressive form of limb-girdle muscular dystrophy type 2C associated with founder mutation in the SGCG gene in Puerto Rican Hispanics. Mol Genet Genomic Med 2015; 3:92-98. 
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